Payroll Manager
Xaira TherapeuticsSouth San Francisco, California, United States · Posted 21 days agoDescription
About Xaira Therapeutics
Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.
About the Role
As the Payroll Manager, reporting directly to the Corporate Controller, you are responsible for overseeing all aspects of payroll administration, ensuring employees are paid accurately, on time, and in compliance with all applicable federal, state, and local regulations. This role manages payroll processes, maintains payroll systems, ensures compliance with tax and labor laws, administers payroll-related benefits and deductions, and partners closely with Human Resources, Accounting, and external payroll providers. This is a hands-on, high-impact role where you will have the unique opportunity to create scalable systems, establish best practices, and drive the development of a robust payroll infrastructure that positions Xaira for long-term success.
Key Responsibilities
Payroll Administration
- Manage the end-to-end payroll process for all employees, including regular payroll, bonuses, and off-cycle payments.
- Ensure timely and accurate processing of multi-state payroll.
- Review payroll registers and perform comprehensive reconciliations across US and UK jurisdictions prior to finalization.
- Maintain payroll calendars and ensure all deadlines are met.
- Process new hires, terminations, salary adjustments, promotions, and other payroll changes.
- Administer Leave of Absence (LOA) payroll calculations, ensuring accurate pay, benefit deductions, statutory leave payments, and return-to-work payroll adjustments in compliance with company policies and applicable federal, state, and local regulations.
- Respond to employee payroll inquiries professionally and confidentially.
- Resolve payroll discrepancies promptly.
Compliance
- Ensure compliance with all federal, state, and local payroll regulations and tax requirements.
- Maintain compliance with wage and hour laws, garnishments, tax levies, and court orders.
- Coordinate payroll tax filings and year-end reporting, including Forms W-2 and related tax documents.
- Support payroll audits and maintain complete payroll documentation.
Accounting & Financial Reporting
- Prepare payroll journal entries and account reconciliations.
- Reconcile payroll liabilities and benefit-related accounts.
- Partner with Accounting during month-end, quarter-end, and year-end close.
- Support internal and external financial audits.
Employee Expense Reimbursements
- Administer the employee expense reimbursement program and ensure timely reimbursement of approved business expenses.
- Review employee expense reports for compliance with company travel and expense policies.
- Verify supporting documentation, coding, receipts, and approvals before processing reimbursements.
- Partner with employees and managers to resolve expense report questions and exceptions.
Corporate Credit Card Administration
- Review corporate credit card transactions for policy compliance, appropriate business purpose, and required supporting documentation.
- Monitor outstanding expense reports and follow up on delinquent submissions.
- Coordinate new card issuance, credit limit changes, and card cancellations with the card provider.
- Investigate and resolve disputed or unauthorized transactions.
- Reconcile monthly corporate credit card statements and support month-end close activities.
Systems & Process Improvement
- Maintain payroll systems and ensure data integrity.
- Partner with Human Resource Team and Accounting teams to improve payroll workflows and automation.
- Recommend and implement process improvements to enhance efficiency and internal controls.
- Maintain payroll policies, procedures, and documentation.
Qualification
- Bachelor's degree in Accounting, Finance, Business Administration, Human Resources, or related field.
- 5+ years of payroll experience, including payroll administration in a multi-state environment.
- Experience administering employee expense reimbursement and corporate credit card programs.
- Strong knowledge of U.S. payroll tax regulations and wage and hour laws.
- Experience with payroll and expense management systems (e.g., ADP, UKG Ready, Concur, Ramp, or similar).
- Advanced Microsoft Excel skills.
- Excellent analytical, organizational, and problem-solving skills.
- Strong attention to detail and ability to handle confidential information.
- Experience with ERP systems such as NetSuite is preferred
Compensation
We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. The base pay range for this position is expected to be $135,000 - $160,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.
Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our
differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.
TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. XairaTherapeutics is not responsible for any fees related to unsolicited resumes.
Similar jobs
Est. 145,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 217,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 166,500 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 287,500 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 261,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 193,500 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 153,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 155,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 107,200 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 153,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 180,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 139,500 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 217,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 165,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 238,500 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 205,000 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 164,000 USD
For more than 25 years, Corcept has been singularly focused on the science of cortisol, a powerful hormone that when unregulated, can play a role in a broad range of diseases. Our commercial portfolio includes treatments…
Est. 160,500 USD
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress…
Est. 139,500 USD
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Est. 109,000 USD
C3 AI (NYSE: AI), is the Enterprise AI application software company. C3 AI delivers a family of fully integrated products including the C3 Agentic AI Platform, an end-to-end platform for developing, deploying, and operat…
Est. 173,000 USD
Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitmen…
Each of us cares about someone who will need medicines. That’s why our vision is to repeatedly beat the odds to deliver breakthrough medicines to patients that need them. We pursue truth and scientific rigour and have th…
Est. 124,959 USD
Our mission: eliminating every barrier to mental health. Spring Health is a global mental health company on a mission to eliminate every barrier to mental health. We're building a world where getting support is simple, p…
Est. 142,500 USD
About AQR Capital Management AQR is a global investment firm built at the intersection of financial theory and practical application. We strive to deliver concrete, long-term results by looking past market noise to ident…
Est. 110,000 USD
About Vercel: Vercel is the agentic infrastructure company. We free people and agents to ship what’s next. For more than a decade, Vercel has shaped how the web is built. As the team behind Next.js, v0, and AI SDK, we cr…
Est. 111,750 USD
Persons in these roles are expected to work from our offices in Seattle. On-site requirements vary based on position and team. If you have questions about on-site work arrangements for this role, please ask your recruite…
Est. 160,000 USD
Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases.…
Est. 148,112 USD
Company Overview ID.me is the next-generation digital identity wallet that simplifies how individuals securely prove their identity online. Consumers can verify their identity with ID.me once and seamlessly login across…
Est. 104,000 USD
About Genetix Biotherapeutics At Genetix Biotherapeutics every role has meaning, every team member is respected, and every day is a chance to make a difference. When you join Genetix, you're not just landing a new role,…
Zenoti provides an all-in-one, cloud-based software solution for the beauty and wellness industry. Our solution allows users to seamlessly manage every aspect of the business in a comprehensive mobile solution: online ap…