Assay Development - Research Associate 2 / Sr. Research Associate
Personalis, IncFremont, California, United States · Posted 7 days agoDescription
At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.
Summary:
In this role, you will collaborate with a multidisciplinary R&D team of scientists, assay developers, and clinicians to plan, execute, and analyze cutting-edge oncology solutions. You will provide hands-on NGS equipment operation and library preparation using real-world samples to develop novel precision medicine products used by pharma, biotech, and clinical partners.
Responsibilities
- Assay & Workflow Execution: Support R&D scientists in developing, optimizing, and validating novel oncology assays and workflows.
- Sample Prep & Library Generation: Extract DNA/RNA from biological samples (blood, tissue) and construct high-quality libraries for Next-Generation Sequencing (NGS).
- Validation & Collaboration Studies: Process sample cohorts for critical assay validation studies and external industry/academic collaborations under tight timelines.
- Protocol Refinement: Evaluate new protocols as a front-line user and provide constructive feedback to optimize standard operating procedures (SOPs).
- Documentation & Reporting: Maintain meticulous sample tracking and experimental records in lab notebooks; present findings in team meetings.
- Compliance: Maintain compliance with safety guidelines, quality standards, and company policies.
Qualifications
- Education: BS/MS in Molecular Biology, Genomics, Biochemistry, or a related biological science.
- Experience: 3+ years of hands-on molecular biology laboratory experience (biotech/pharma preferred).
- Technical Expertise: Proficiency in DNA/RNA extraction, quality control (e.g., Qubit, TapeStation), and NGS library preparation.
- Assay Specialization: Experience with liquid biopsy (cfDNA/cfRNA) or FFPE sample processing is strongly preferred.
- Skills & Drive: Strong organizational and communication skills with a drive to learn in a fast-paced, hands-on environment
The hiring range for this position is $85,000 to $115,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.
Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.
Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.
Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)
#LI-KK1 #LI-Hybrid
Similar jobs
Est. 100,000 USD
At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient…
Est. 120,500 USD
At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient…
Est. 162,500 USD
At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient…
Est. 150,000 USD
At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient…
Est. 69,450 USD
At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient…
Est. 124,800 USD
At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient…
Est. 181,440 USD
At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient…
Est. 85,000 USD
About this opportunity: At Freenome, we are seeking a Senior Research Associate to help grow our Genomics Assay Development team. At Freenome, you will help develop the assay technologies used to analyze patient samples…
Est. 93,760 USD
About this opportunity: At Freenome, you will help develop the assay technologies used to analyze patient samples and contribute to our mission of early detection and intervention in human disease. As a Research Associat…
Est. 187,500 USD
At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient…
Est. 94,312 USD
About this opportunity: At Freenome, you will help develop the assay technologies used to analyze patient samples and contribute to our mission of early detection and intervention in human disease. As a Research Associat…
Est. 140,000 USD
About this opportunity: At Freenome, we are seeking a Senior Development Scientist I to help grow the Freenome Genomics Late Development team. You will develop, optimize, verify, and validate clinical-grade assay technol…
Est. 111,925 USD
About this opportunity: At Freenome, we are seeking a Senior Research Associate to help grow the Freenome Genomic Early Development team. As a Senior Research Associate, you will participate in the development of genomic…
Est. 149,763 USD
About this opportunity: At Freenome, you will help develop the assay technologies used to analyze patient samples and contribute to our mission of early detection and intervention in human disease. As a Research Scientis…
Est. 49,920 USD
At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient…
Est. 156,194 USD
A Rare Opportunity to Shape the Future of Genomics Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq w…
Est. 53,500 USD
POSITION DURATION: This is a six-month contract role located in San Carlos with the potential to extend or convert to full-time based on performance and business needs. POSITION SUMMARY: Join our dynamic and fast-paced a…
Est. 115,247 USD
A Rare Opportunity to Shape the Future of Genomics Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq w…
Est. 78,500 USD
POSITION SUMMARY: The Product Development Sr. Research Associate will contribute to the design, execution and participation in experiments/tasks to support oncology product development and verification and validation (V&…
Est. 76,480 USD
At Veracyte, we offer exciting career opportunities for those interested in joining a pioneering team that is committed to transforming cancer care for patients across the globe. Working at Veracyte enables our employees…
Est. 82,589 USD
A Rare Opportunity to Shape the Future of Genomics Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq w…
Est. 80,285 USD
A Rare Opportunity to Shape the Future of Genomics Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq w…
Est. 252,500 USD
Associate/Laboratory Director of Oncology, Comprehensive Genomic Profiling Position Summary As an Associate Lab Director or Lab Director of Oncology, you have clinical oversight of Natera’s laboratory testing related to…
Est. 229,325 USD
About this opportunity: At Freenome, we are seeking a Staff Computational Biologist to help grow the Freenome Computational Biology, Assay Research (CBAR) team. As part of our team, you will apply your scientific experti…
Est. 127,500 USD
POSITION SUMMARY: The Oncology Pathology Assistant provides assistance to the Signatera team as a subject matter expert for review of clinical pathology reports and clinical notes. The Oncology Pathology Assistant will a…
Est. 84,425 USD
About Alltrna Alltrna is the first clinical-stage biotech company advancing tRNA medicines to address shared disease-causing mutations across many indications. The company’s initial therapeutic programs are designed to r…
Est. 227,500 USD
As the Associate/Laboratory Director, Oncology and one of our Laboratory Directors, you have clinical oversight of Natera’s laboratory testing. You ensure that testing is properly performed, and applicable regulatory sta…
Est. 150,850 USD
POSITION SUMMARY As the Laboratory Director and one of our Laboratory Directors, you have clinical oversight of Natera’s laboratory testing. You ensure that testing is properly performed, and applicable regulatory standa…
Est. 152,500 USD
Rapidly Growing Life Sciences Technology Company Ultima Genomics is a rapidly growing company that is developing ground-breaking genomics technologies. Our mission is to continuously drive the scale of genomic informatio…
Est. 92,775 USD
POSITION SUMMARY: Join Natera’s Oncology Research Use Only (RUO) team as a Supervisor for the Signatera Plasma Team. You will direct laboratory staff executing cell-free DNA (cfDNA) extraction, library preparation, and N…